The final episode of the spring anime ‘The Apothecary Diaries’! Jinshi and Nekone reunite. What did Rouran risk his life to protect, and what did he entrust to Nekone? Episode 48 advance cut

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The synopsis and preview scene cuts of the 48th episode, “The Beginning,” the final episode of the 2nd season of the spring anime “The Apothecary Diaries,” which will be broadcast on Friday, July 4, 2025, have been released.

“The Apothecary Diaries” is a harem mystery-solving entertainment series based on a novel that has sold over 40 million copies worldwide. Natsu Hinata is currently publishing it from “Hero Bunko” and is also being adapted into a comic in “Big Gangan” and “Sunday GX.” Set in the medieval Orient, the story follows the young girl Nekoneko, a “poison taster,” as she solves a series of complex cases that arise in the palace one after another.

The second season of the TV anime, which began airing in January 2025, has garnered attention, consistently ranking high on various distribution platforms, and it premiered in April. In the “Anime and Manga Awards that Fans Are Hot About,” announced in May, this work won the grand prize in the currently airing anime category, and Ikuta Rira’s “Hyakka Ryoran,” the opening theme song for the first season, won the grand prize, achieving a double crown.

It also won the manga and anime category and the grand prize in the “TikTok First Half Trend Awards 2025,” showing excitement. Episode 48 “The Beginning” Synopsis: At dawn, after the suppression of the Ko clan was over, Jinshi came to Nekoneko, who was sleeping with the children who had been carried out of the fort.

While worrying about each other’s wounds, they each began to think about what Loulan had risked his life to protect and what he had entrusted to them. Episode 48 of “The Beginning,” the second season of “The Apothecary Diaries,” will begin airing on Nippon Television’s “FRIDAY ANIME NIGHT (Fura-ani)” from 11:00 p.m. on Friday, July 4.

TV anime “The Apothecary Diaries” work summary [Broadcast information] TV anime “The Apothecary Diaries” will be broadcast nationwide on Nippon Television’s “FRIDAY ANIME NIGHT” every Friday from 11:00 p.m.! After the Broadcast, it will be distributed on various distribution platforms!

Broadcast dates and times are subject to change without notice.

[Staff] Original work: Hinata Natsu (Hero Bunko/Imagica Infos) Character design: Shino Touko General director/series composition: Naganuma Norihiro Director: Fudesaka Akinori Assistant director: Nakagawa Wataru Script: Kakihara Yuko, Chiba Misuzu, Ogawa Hitomi Character design: Nakatani Yukiko Art director: Takao Katsumi (ARED) Color design: Aida Misato CGI director: Nagai Yu Director of photography: Suzuki Mayo (T2 studio) Editing: Imai Daisuke Sound director Hata Shoji (Sound Team Don Juan) Music: Kanzaki Akira, Kevin Penkin, Okehazama Arisa Second season opening theme: Mrs. GREEN APPLE “Kusushiki” Second season ending theme: Omoinotake “Hitorigoto” Animation production: TOHO animation STUDIOƗOLM Production: “The Apothecary Diaries” Production Committee

[Cast] Nekoneko/Yuki Aoi Jinshi/Otsuka Takeo Takayoshi/Konishi Katsuyuki Princess Tamaba / Atsumi Tanezaki Princess Rika / Yui Ishikawa Princess Satoki / Hina Kino Koran / Misaki Kuno Kosui / Masami Seto Narration / Sumi Shimamoto (C) Natsu Hinata, Imagica Infos / “The Pharmacist’s Monologue” Production Committee

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